751-1 Efficacy of Tranilast on Restenosis After Coronary Angioplasty: is There Any Rebound Phenomenon After Ceasing Tranilast at 3 Months?
نویسندگان
چکیده
منابع مشابه
Inhibition of neointima formation by tranilast in pig coronary arteries after balloon angioplasty and stent implantation.
OBJECTIVES We evaluated the effect of orally administered tranilast, N-(3,4-dimethoxycinnamoyl) anthranilic acid, on histologic and histomorphometric changes after angioplasty or stent implantation in pig coronary arteries. BACKGROUND Tranilast, which has antikeloid and antiallergic properties and therefore may modulate the fibrotic and inflammatory tissue responses to angioplasty and stentin...
متن کاملClinical trials of restenosis after coronary angioplasty.
Since its introduction more than 10 years ago, coronary angioplasty has been limited by a 30-40% incidence of restenosis, typically developing within 3-6 months of the procedure.12 The interactive biological processes responsible for re-stenosis have generally been attributed to varying degrees of three pathological mechanisms. First, depending on the relative fibrocellular, sclerotic, and calc...
متن کاملImpact of cilostazol on restenosis after percutaneous coronary balloon angioplasty.
BACKGROUND Restenosis after percutaneous transluminal coronary (balloon) angioplasty (PTCA) remains a major drawback of the procedure. We previously reported that cilostazol, a platelet aggregation inhibitor, inhibited intimal proliferation after directional coronary atherectomy and reduced the restenosis rate in humans. The present study aimed to determine the effect of cilostazol on restenosi...
متن کاملInfluence of intimal dissection on restenosis after successful coronary angioplasty.
We studied 986 patients who underwent follow-up angiography after successful percutaneous transluminal coronary angioplasty (PTCA) to determine the influence of uncomplicated intimal dissection on restenosis rate. Angiographic evidence of intimal dissection after PTCA was present in 248 patients or 25%. After a mean follow-up time of 7 +/- 5 months (SD) the restenosis rate in patients without i...
متن کاملN-3 fatty acids do not prevent restenosis after coronary angioplasty: results from the CART study. Coronary Angioplasty Restenosis Trial.
OBJECTIVES The aim of the study was to investigate whether omega-3 fatty acids (n-3 FA) reduce the occurrence of restenosis after percutaneous transluminal coronary angioplasty. BACKGROUND Meta-analyses have shown significant reduction of restenosis after coronary angioplasty upon supplementation with n-3 FA. METHODS In a prospective, placebo-controlled, double-blind study, 500 patients wer...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1995
ISSN: 0735-1097
DOI: 10.1016/0735-1097(95)92396-m